Which agency focuses on the reduction of threats to national security?

The Defense Threat Reduction Agency (DTRA) is primarily focused on reducing threats to national security, particularly those posed by weapons of mass destruction (WMD) and emerging threats. This agency plays a critical role in preventing the proliferation of nuclear, chemical, and biological weapons and enhancing the nation's ability to respond to such threats. It conducts research, develops capabilities, and provides support for defense strategies aimed at mitigating the risks associated with these dangerous materials.

In contrast, the other agencies listed serve different functions: the Defense Information Systems Agency (DISA) focuses on providing information technology and communications support for the Department of Defense; the Defense Logistics Agency (DLA) is responsible for logistics and supply chain management; and the National Geospatial-Intelligence Agency (NGA) specializes in geospatial intelligence and mapping services. Hence, DTRA's focus on threat reduction aligns specifically with the question regarding national security threats.